Sunil Pradhan
Sunil Pradhan | |
---|---|
Born | Shanti Swarup Bhatnagar Prize Dr. B. C. Roy Award Uttar Pradesh Vigyan Ratna Dr. H. B. Dingley Memorial Award Shakuntala Amirchand Memorial Award Rajib Goyal Award Amrut Modi Unichem Award Maj Gen. Amir Chand Award Dr. S. T. Achar Award Best Poster Paper Award Best Paper Award Vocational Excellence Prize | 25 June 1957
Website | Official web site |
Sunil Pradhan (born 25 June 1957) is an Indian
Biography
Dr. Pradhan's extensive clinical research in the area of muscular dystrophy has led to the discovery of five new clinical signs, each indicative of a specific type of the disease.
Sanjay Gandhi Post Graduate Institute of Medical Sciences circular.[1]
Pradhan was born in the hill station of
Pradhan started his career at
Pradhan brought about many changes at the IHBAS. He was instrumental in updating and elaborating the signage, displays and boards and constructing patient shelters. The electrophysiology Lab was started where he arranged for the setting up of modern equipment like 32 Channels Polysomnography, Nicolet 32 Channels digital Portable Electroencephalography and Electromyography.
Pradhan lives in Lucknow, along the
Legacy
The legacy of Pradhan centres primarily around the five
Medical signs
Pradhan sign or Valley sign: The first of the signs he discovered is related to
Poly hill sign: Poly Hill Sign,[8] the second of the signs Pradhan discovered related to facioscapulohumeral muscular dystrophy(FSHD).[6] Pradhan noticed that the shoulder abduction of a patient with external rotation resulted in the formation of six bulges on the back of the shoulders and arms and named it poly hill due to the bulges.[1] He has also reported of an extra hill in one of the cases he attended to.[9]
Shank sign: The third sign, Shank Sign,[10] is related to myotonic dystrophy type 1 (DM-1). When patients suffering from the disease abduct their arms to 90 degrees, a tapering of the upper arm musculature is observed when examined from behind, due to wasting of the biceps, triceps and forearm muscles. This gives a visual resemblance of the shanks of an animal. This sign had an occurrence on 78% of the patients examined by Dr. Pradhan.[6][10]
Calf-head sign:
Diamond on quadriceps sign: The sign is related to
Electrophysiological techniques
Pradhan is credited with two new techniques related to electrophysiology.[1]
The first technique is related to the non-invasive study of intercostal nerves.
The second technique involves stimulating the intercostal nerves to study the somatosensory evoked potentials, for localizing the non compressive spinal cord lesions.[14]
Pradhan was successful in elucidating the mechanisms of neurophysiological F‑response generation in healthy and diseased bodies and discovered a phenomenon, F-response multiplicity, a symptom of the lower motor neuron disorder. Pradhan asserted, by way of his findings, loss of early components and scattering of late components are responsible for the different F-response parameters in the lower neuron disorders.[1] He has also demonstrated standardized variables of contraction enhanced H‑reflex called R‑1 response and its utility in nerve root lesions where H-reflex is not electable. This was ratified by many researchers.[1]
Research on Japanese Encephalitis
Pradhan found out that the Japanese‑B encephalitis (JE) sometimes produced selective lesions on the substrata nigra and this observation has assisted in eliciting a clue in explaining the early onset of
Research on Epilepsy
Pradhan has done extensive research on epilepsy.[16] His studies revealed that patients are likely to suffer from chronic epileptogenesis with poor seizure outcome if gliosis is present around their lesions. He averred that the patients with neurocysticercosis are prone to developing perilesional gliosis, may develop drug resistance during anti‑epileptic drug (AED) therapy and may suffer seizures if the drug is stopped. He has also explained tickling seizures[17] and micturition induced reflex epilepsy,[18] both reported to be first time findings.[1]
Research on Hirayama type Monomelic Amyotrophy
Pradhan has done research on Hirayama type monomelic amyotrophy,[19] a disease described by Dr. Hirayama in 1959.[20] In 1977, he published a report explaining the features of diagnostic magnetic resonance imaging.[1] The diagnosis of the disease remaining purely clinical, it is reported that his findings are the only objective diagnostic method. Dr. Hirayama, in 2003, published a paper confirming Dr. Pradhan's findings.[1]
Other studies
Pradhan is also credited with other findings such as:
- If the process is of long duration, patients may develop central
- Explanation of the sheathing of the retinal vessels in
- Description of MRI and other features of acute endosulphan poisoning and its similarities with the MRI features of Huntington's disease and suggested neurotoxic mechanism by blocking mitochondrial energy metabolism.[1][23]
- Description of a new method for extracting lipid from muscle tissues for NMR studies.[24]
- Description of micturition induced reflex epilepsy.[18]
- Classification of acute transverse myelitis.[25]
Awards and recognitions
The Government of India, in 2014, honoured Dr. Sunil Pradhan, by awarding him the civilian honour of Padma Shri.[4] He has received many other awards such as:
- Shanti Swarup Bhatnagar Prize - Council for Scientific and Industrial Research - Government of India - 2002[1][2][5]
- Dr. B. C. Roy Award - Medical Council of India - 2003
- Uttar Pradesh Vigyan Ratna - Council of Science and Technology - Government of Uttar Pradesh - 2003-04[2][5]
- Dr. H. B. Dingley Memorial Award - Indian Council of Medical Research - 1994 and 1996[1][2][5]
- Shakuntala Amirchand Memorial Award - Indian Council of Medical Research - 1999[2][5]
- Rajib Goyal Award - Kurukshetra University - Haryana - 2003[5][26]
- Amrut Modi Unichem Award - Indian Council for Medical Research (ICMR) - 2007[6]
- Maj Gen. Armed Forces Medical College, Pune - 1998[5]
- Dr. S. T. Achar Award - Indian Academy of Pediatrics - 1995[1][5]
- Dr. S. T Achar Award - Indian Academy of Pediatrics - 1996[1][5]
- Best Poster Paper Award - Indian Academy of Neurology - 1993[5]
- Best Paper Award - Indian College of Radiology - 1999[5]
- Vocational Excellence Prize - Rotary International - 2002[5]
- Elected fellowship - National Academy of Medical Sciences (2006)[27]
Sunil pardhan_007
Pradhan has published several research papers in peer reviewed journals, both national and international in circulation.[28] A random selection of his articles features:
- Levac, Danielle; Espy, Deborah; Fox, Emily; Pradhan, Sujata; Deutsch, Judith E. (1 March 2015). "'Kinect-ing' With Clinicians: A Knowledge Translation Resource to Support Decision Making About Video Game Use in Rehabilitation". Physical Therapy. 95 (3): 426–440. PMID 25256741.
- Snoussi, Karim; Gillen, Joseph S.; Horska, Alena; Puts, Nicolaas A. J.; Pradhan, Subechhya; Edden, Richard A. E.; Barker, Peter B. (September 2015). "Comparison of brain gray and white matter macromolecule resonances at 3 and 7 Tesla: MRS of Brain Macromolecules at 3T and 7T". Magnetic Resonance in Medicine. 74 (3): 607–613. PMID 25252131.
- Pradhan, Sunil; Kumar, Ajit (2014). "Lower motor neuron paralysis with extensive cord atrophy in parainfectious acute transverse myelitis". Annals of Indian Academy of Neurology. 17 (3): 347–8. PMID 25221410.
- Pradhan, Sunil K.; Kamble, Nitin M.; Pillai, Aravind S.; Gaikwad, Satish S.; Khulape, Sagar A.; Reddy, M.R.; Mohan, C. Madhan; Kataria, Jag Mohan; Dey, Sohini (December 2014). "Recombinant nucleocapsid protein based single serum dilution ELISA for the detection of antibodies to infectious bronchitis virus in poultry". Journal of Virological Methods. 209: 1–6. PMID 25173423.
- Pradhan, S (June 2004). "Valley sign in Becker muscular dystrophy and outliers of Duchenne and Becker muscular dystrophy". Neurology India. 52 (2): 203–5. PMID 15269471.
The National Center for Biotechnology Information of the United States National Library of Medicine has published the abstracts of over 750 papers published by Dr. Pradhan.[28] Nanojamians, a blog providing information on technological advancement in neuro sciences, has also listed many of his papers.
Controversy
It was around 12 noon on Monday when the judge came to the OPD and asked to be seen by me. As is the normal procedure, I requested that the case should first go to a resident doctor for preparation of a medical case sheet. But he insisted to be seen by me only. He carried no medical file with him. Also, no doctor had referred him to me. Anyway, I called him in. As I was busy seeing a patient, I could only offer a chair to the lady accompanying the judge. I did not have more chairs to offer to the judge. He, however, left, Dr. Pradhan said about the incident.[2]
On 9 October 2006, Dr. Pradhan received a
Later, acting on the news report, the Governor of Uttar Pradesh,
References
- ^ a b c d e f g h i j k l m n o p q r s t u v w x y z "CSIR". Central Council of Industrial Research. 30 June 2003. Retrieved 2 October 2014.
- ^ a b c d e f g "Controversy". Hindustan Times. 10 October 2006. Retrieved 1 October 2014.
- PMID 7702689.
- ^ a b "Padma Awards Announced". Circular. Press Information Bureau, Government of India. 25 January 2014. Archived from the original on 22 February 2014. Retrieved 23 August 2014.
- ^ a b c d e f g h i j k l m n "Vidhwan". Vidhwan. 2014. Retrieved 1 October 2014.
- ^ a b c d e f g "TOI". TOI. 7 November 2011. Retrieved 1 October 2014.
- PMID 12134184.
- S2CID 45754265.
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- ^ S2CID 21870075.
- ^ PMID 17030657.
- S2CID 10645075.
- PMID 2526200.
- PMID 12700306.
- S2CID 25764800.
- S2CID 24449302.
- PMID 29542652.
- ^ PMID 29542670.
- PMID 22566723.
- PMID 17665029.
- S2CID 12090766.
- PMID 1822694.
- S2CID 28905740.
- S2CID 95137864.
- PMID 12122174.
- ^ "Tribune". Tribune India. 4 February 2003. Retrieved 2 October 2014.
- ^ "List of Fellows - NAMS" (PDF). National Academy of Medical Sciences. 2016. Retrieved 19 March 2016.
- ^ a b Search Results for author Pradhan S on PubMed.
- ^ "Highbeam Research". Highbeam Research. 11 October 2006. Archived from the original on 23 March 2015. Retrieved 2 October 2014.
External links
- "NANOJAMIANS: A PROUD OF NEUROLOGY". nanojamians.blogspot.in. 22 February 2009. Retrieved 27 July 2015.